Clinical Features and Neuroimaging Findings in Patients with Cerebral Fat Embolism
نویسندگان
چکیده
IntroductIon Cerebral fat embolism (CFE) is a rare but potentially lethal disease that is usually complicated by long bone fracture, which can develop over 12–72 h. Since the main form of treatment for CFE is supportive, early diagnosis, prevention, and appropriate treatment can reduce mortality and the development of complications. However, due to symptom heterogeneity and imprecise diagnostic methods, CFE may be masked by other clinical conditions that make early detection challenging. Given its low incidence, most clinical studies of CFE are single cases or small case series. To characterize the features of CFE, clinical manifestations, laboratory examinations, and neuroimaging data were evaluated in a large sample of patients with CFE.
منابع مشابه
Incidence of fat embolism syndrome in patients with long bone and/or pelvic fracture admitted to Shahid Bahonar hospital in Kerman
this study was carried out from October 1993 through November 1995(26 months).during this period 3472 patients(2743 male and 729 female) with long bone and/or pelvic fracture were admitted in different wards of Shahid Bahonar hospital of Kerman.based on the Gurd criteria,25 of these patients (24 male,1 female) were suffering from fat embolism sundrome(FES).incidence of FES in this study was ...
متن کاملNeuroradiologic findings in polyarteritis nodosa.
PURPOSE To demonstrate the neuroradiologic findings in patients with polyarteritis nodosa. METHODS A review of hospital records for a 10-year period revealed 50 patients with a discharge diagnosis of polyarteritis nodosa. Thirteen patients had undergone neuroimaging, and abnormal findings were found in 5 cases; these were the subjects of this study. RESULTS All 5 patients had abnormal findi...
متن کاملGradient-Echo MRI in Defining the Severity of Cerebral Fat Embolism
BACKGROUND A few studies have found that abnormal findings on diffusion-weighted magnetic resonance imaging (MRI) are useful for diagnosing cerebral fat embolism in the acute stage. CASE REPORT We applied serial MRI to a case of cerebral fat embolism with cognitive impairment lasting for 2 months. Although marked resolution of the previous abnormal findings was demonstrated, T2*-weighted grad...
متن کاملEfficacy of Corticosteroids in Prevention of Fat Embolism Syndrome in Patients with Long Bone Fracture
Fat embolism syndrome refers to a constellation of symptoms secondary to the presence of fat globules in the lung parenchyma and/or peripheral blood circulation. The syndrome is most often seen in association with long bone or pelvic fractures and can cause significant morbidity and mortality. The present randomized double blind placebo-controlled trial was conducted to evaluate the efficacy of...
متن کاملRestricted diffusion and poor clinical outcome in cerebral fat embolism syndrome.
Cerebral fat embolism syndrome (CFES) is a neurologic syndrome occurring in up to 60% of patients with fat embolism syndrome (FES). The defining features of FES include respiratory, neurologic and dermatologic features. The classical explanation is release of fat emboli into the circulation after long bone fractures, but the clinical syndrome of FES only occurs in 0.5-3% of cases, typically wit...
متن کامل